I originally had this card and it seemed to work fine with the GBPVR release I was using at the time. I think the only issue I had is that it would only record with a Constant Bit Rate (not VBR), but that didn't really matter to me. I did however change to a Hauppauge PVR350 card because my computer was too slow for MPEG2 playback.
Overall though, I suggest that if you haven't bought the card, go for one of the Hauppauge ones as you'll find support from this forum to be better, and are more likely to continue working as sub evolves GBPVR.
Server: NPVR 2.2.6, Asus E35M1-M PRO motherboard, 2 x 2GB DDR-1333 memory, 1 x 1.5TB SATA Samsung HD, 2 x 2TB SATA Seagate Green HD, 1 x Hauppauge HD4400, 2 x Hauppauge Nova T 500, Windows 7 Home.
Clients: EGreat M34A with MVPMCX2; HDX1000 with MVPMCX2 and internal 2TB SATA Seagate Green HD.